Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Author: Martine Aliana Rothblatt
Publisher: Temple University Press
How will we handle baby-making and pregnancy in the next 5, 25, and 75 years? New reproductive technology, genetic screening, and DNA-mapping have changed the 20th-century rules. In this revolutionary manifesto, Martine Rothblatt proposes a code of ethics to guide childbirth decisions in the brave new world of biotechnology.The trigger for Unzipped Genesis the Human Genome Project, a multibillion dollar effort to unlock the secrets of the human genetic code. This new "genomic" knowledge can be used for tremendous good, such as curing disease, or unprecedented harm, such as the kinds of master race eugenics already visible in Asia, where social pressures force families to choose to abort female fetuses. Without a bioethics of birth, we risk creating a new kind of racism, which Rothblatt calls "genism," based on officially sanctioned genetic characteristics. Unregulated genetic decision-making can open the door to invasion of privacy, efforts to eliminate certain kinds of people from the gene pool, or government or corporate efforts to gain control of the human genome.Rothblatt bases her bioethics of birth on four principles designed to empower the beneficial potential of genomics without unleashing genism. First, we must agree that the human genome belongs indivisibly to us all. Second, we must allow each person an unfettered right to intentionally create in his or her children new versions of the genome without limitations on its genetic characteristics. Third, we must insist that society has a right to help prevent unwanted pregnancies. And finally, we must ensure that genetically influenced characteristics -- from skin tone to predispositions to disease, from sexual orientation to various mental inclinations -- will not be the basis of discrimination of any kind.Writing concretely and persuasively, Rothblatt explains the biotechnology of the Human Genome Project in terms we all can understand. Not limiting her bioethics to the realm of abstraction, she maintains that her new bioethics of birth will lead to the end of abortion and unwanted pregnancy and the creation of a world in which people can achieve a greater solidarity with one another. Author note: Martine Rothblatt is an international high-tech lawyer and speaker on bioethics in Washington, D.C. She is also the Chairperson of the Bioethics Subcommittee of the International Bar Association and the author of The Apartheid of Sex.
The Selfish Gene
Author: Richard Dawkins
Publisher: Oxford University Press, USA
An ethologist shows man to be a gene machine whose world is one of savage competition and deceit
Genes & Genomes
Author: Maxine Singer, Paul Berg
Publisher: University Science Books
This overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms emphasizes the experimental aspects of molecular genetics. It provides a complete introduction to both principles and methods.
Author: Barbara Oakley
Publisher: Prometheus Books
Have you ever heard of a person who left you wondering, "How could someone be so twisted? So evil?" Prompted by clues in her sister’s diary after her mysterious death, author Barbara Oakley takes the reader inside the head of the kinds of malevolent people you know, perhaps all too well, but could never understand. Starting with psychology as a frame of reference, Oakley uses cutting-edge images of the working brain to provide startling support for the idea that "evil" people act the way they do mainly as the result of a dysfunction. In fact, some deceitful, manipulative, and even sadistic behavior appears to be programmed genetically—suggesting that some people really are born to be bad. Oakley links the latest findings of molecular research to a wide array of seemingly unrelated historical and current phenomena, from the harems of the Ottomans and the chummy jokes of "Uncle Joe" Stalin, to the remarkable memory of investor Warren Buffet. Throughout, she never loses sight of the personal cost of evil genes as she unravels the mystery surrounding her sister’s enigmatic life—and death. Evil Genes is a tour-de-force of popular science writing that brilliantly melds scientific research with intriguing family history and puts both a human and scientific face to evil. From the Hardcover edition.
Author: Gordon Graham
Publisher: Psychology Press
'It's all in the genes'. Is this true, and if so, what is all in the genes? Genes: A Philosophical Inquiry is a crystal clear and highly informative guide to a debate none of us can afford to ignore. Beginning with a much-needed overview of the relationship between science and technology, Gordon Graham lucidly explains and assesses the most important and controversial aspects of the genes debate: Darwinian theory and its critics, the idea of the 'selfish' gene, evolutionary psychology, memes, genetic screening and modification, including the risks of cloning and 'designer' babies. He considers areas often left out of the genes debate, such as the environmental risks of genetic engineering and how we should think about genes in the wider context of debates on science, knowledge and religion. Gordon Graham asks whether genetic engineering might be introducing God back into the debate and whether the risks of a brave new genetic world outweigh the potential benefits. Essential reading for anyone interested in science, technology, and philosophy, Genes: A Philosophical Inquiry is ideal for those wanting to find out more about the ethical implications of genetics and the future of biotechnology.
Introduces genes, describes the structure of chromosomes and disorders that occur from mutations or alterations, and discusses the practice and application of genetic engineering.
Author: Jonathan Slack
Publisher: Oxford University Press, USA
Explores the discovery, nature, and role of genes in evolution and development.
What's in Your Genes?
Author: Katie McKissick
Publisher: Simon and Schuster
A crash course in genetics! Everyone knows that if you come from a family of brunettes, you're likely to be born with brown hair. But did you know your hair color may also affect how often you get sunburned? Or how often you need to take vitamin supplements? What's in Your Genes? goes beyond Gregor Mendel and dominant/recessive genes to show you all the ins and outs of what determines your DNA. Each entry provides you with a sneak peek into your DNA sequence and teaches you exactly how your body is able to create that wonderful you-ness that no one else has. From your tastebuds to your eye color to your obsession with clinical-strength deodorants, this book not only guides you through the history and study of genetics, but also shows you how those four little letters in your DNA make you who you are. Complete with imaginative illustrations, What's in Your Genes? reveals all there is to know about heredity--like the science behind vibrant red hair, perfect teeth, and your ability to see in color.
First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.
Author: Deepak Chopra, M.D., Rudolph E. Tanzi, Ph.D.
The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled. "You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting." Learning how to shape your gene activity is at the heart of this exciting and eagerly-anticipated book from the bestselling duo behind Super Brain, which became a nationwide hit on public television. For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago. The impact on prevention, immunity, diet, aging, and chronic disorders is unparalleled.
Genes, Development and Cancer
Author: Howard D. Lipshitz
Publisher: Springer Science & Business Media
This second edition collects Nobel Prize winner Edward B. Lewis’s key publications in the fields of genetics, developmental biology, radiation and cancer. Editor Howard Lipshitz, a close colleague during the last 20 years of Lewis's life, places the papers in their scientific and historical context and provides insight into Lewis's approach to science and the motivations that drove his choice of subject matter.
L. Luca Cavalli-Sforza and his collaborators Paolo Menozzi and Alberto Piazza have devoted fourteen years to one of the most compelling scientific projects of our time: the reconstruction of where human populations originated and the paths by which they spread throughout the world. In this volume, the culmination of their research, the authors explain their pathbreaking use of genetic data, which they integrate with insights from geography, ecology, archaeology, physical anthropology, and linguistics to create the first full-scale account of human evolution as it occurred across all continents. This interdisciplinary approach enables them to address a wide range of issues that continue to incite debate: the timing of the first appearance of our species, the problem of African origins and the significance of work recently done on mitochondrial DNA and the popular notion of an "African Eve," the controversy pertaining to the peopling of the Americas, and the reason for the presence of non-Indo-European languages--Basque, Finnish, and Hungarian--in Europe. The authors reconstruct the history of our evolution by focusing on genetic divergence among human groups. Using genetic information accumulated over the last fifty years, they examined over 110 different inherited traits, such as blood types, HLA factors, proteins, and DNA markers, in over eighteen hundred, primarily aboriginal, populations. By mapping the worldwide geographic distribution of the genes, the scientists are now able to chart migrations and, in exploring genetic distance, devise a clock by which to date evolutionary history: the longer two populations are separated, the greater their genetic difference should be. This volume highlights the authors' contributions to genetic geography, particularly their technique for making geographic maps of gene frequencies and their synthetic method of detecting ancient migrations, as for example the migration of Neolithic farmers from the Middle East toward Europe, West Asia, and North Africa. Beginning with an explanation of their major sources of data and concepts, the authors give an interdisciplinary account of human evolution at the world level. Chapters are then devoted to evolution on single continents and include analyses of genetic data and how these data relate to geographic, ecological, archaeological, anthropological, and linguistic information. Comprising a wide range of viewpoints, a vast store of new and recent information on genetics, and a generous supply of visual elements, including 522 geographic maps, this book is a unique source of facts and a catalyst for further debate and research.
Many historical events such as invasions, wars, civil unrests, migrations, and religious conversions have shaped the genetic heritage of India. These events created a potpourri of cultures and genes. The invaders came from Central Asia, Afghanistan, Arabia, Iran, Greece, Britain, France, and Portugal to loot and plunder wealth, but also left their genes behind among Indians irrespective of their caste or creed. The origin and migration of early man from Africa across the planet, the impact of the caste system and Indian religions on restricting gene flow, and the repeated breakdown of the caste system during the past 5,000 years are explained in Invasion of the Genes. A biologist and a geneticist, Prof. B.S. Ahloowalia says the prime motivation in writing the book was based on observing the similarity in culture, language, and resemblance of physical features between people of Persia, Arabia and North India. Dr. Ahloowalia did his Ph.D. from University of Chicago, and worked for the Agriculture and Food Development Authority, Dublin, Ireland. Later, he also worked for the International Atomic Energy Agency and Food and Agriculture Organization of the United Nations.
Author: Daniel L. Hartl, Elizabeth W. Jones
Publisher: Jones & Bartlett Learning